A novel pathway for exotoxin delivery by an intracellular pathogen
نویسندگان
چکیده
منابع مشابه
Delivery of a Salmonella Typhi exotoxin from a host intracellular compartment.
Salmonella Typhi, an exclusive human pathogen and the cause of typhoid fever, expresses a functional cytolethal distending toxin for which only the active subunit, CdtB, has been identified. Here, we show that PltA and PltB, which are encoded in the same pathogenicity islet as cdtB, associate with CdtB to form a multipartite toxin. PltA and PltB are homologs of components of the pertussis toxin...
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ژورنال
عنوان ژورنال: Current Opinion in Microbiology
سال: 2008
ISSN: 1369-5274
DOI: 10.1016/j.mib.2007.12.002